Vitiligo or Pes – acquired disorders of pigmentation of the skin characterized by the appearance of any part of it, except the palms and soles, clearly defined, devoid of pigment spots round or irregular in shape, surrounded by rim of hyperpigmentation. According to the cosmetology, vitiligo is 3-4% of all dermatoses. The disease is not accompanied by subjective feelings, but is a cosmetic defect and, if depigmented spots located on exposed skin, especially on the face, hurt psyche patient. The disease begins at a young age, often occurs in children. The etiology and pathogenesis of vitiligo in the present study did not to the end. The pigment melanin is produced in the skin of humans and animals to adapt and protect against ultraviolet radiation (UVR). It is synthesized from tyrosine in the melanocytes, have large numbers of organemelanosom containing melanin, which is concentrated around the nucleus keratinatsitov. In the presence of the enzyme tyrosinase tyrosine formed initially dihydroxyphenylalanine, then dioksifenilalaninhinon.

To activate the tyrosinase requires molecular oxygen, copper ions and UV irradiation. Copper ions and UV effect on lysosomal enzymes that degrade glutathione, peptidase-blocking tyrosinase. Polymerization products of oxidation of tyrosine takes place in the presence zinc ions. In cells, melanin is not in the free state and bound to proteins in the form of melanoproteina. At the beginning of the disease melanocytes still retained, but do not produce pigment. Over time, foci of depigmentation they almost completely disappear, with the exception of hyperpigmented rim on the periphery, where the activity of melanocytes and melanin content podvysheno.

Pangamic acid (vitamin B15) is found in the embryonic seeds of many plants and sprouts, almonds and other stone fruit kernels. The content of vitamins in the wild fruit and berries is low, and in this respect they differ little from their cultural counterparts. And they both are not the source, and can only be an additional reserve of these vitamins. Folic acid (vitamin B9) is rich in strawberries, with its associated beneficial than effect of anemia. More of a raspberry. It is also found in apples, apricots, black currants and other valuable property of vitamin B15 – the ability to attenuate a side effect of some toxic and medicinal preparations by-products produced in the body during metabolism. Vitamin successfully used in complex therapeutic agents for certain heart diseases, arteriosclerosis, rheumatism and liver diseases. Vitamin K helps blood to clot when bleeding.

Nowadays you can clean the pillows on the professional equipment for cleaning pads. Diseases associated with lack of food in vitamin K, practically do not occur, so as it is produced by bacteria in the gut. Vitamin found in nettles, spinach, apples, etc. Vitamin E has a very high antioxidant activity. It improves digestion and absorption of vitamin A, has stimulating effect on the muscular system. In significant amounts contained in sea-buckthorn, dog rose, apple, plum and other alkaloids.

The most important group of biologically active substances are alkaloids – substances produced by plants and represent a complex nitrogen-containing compounds. Need cleaning pads. Currently have about 5000 different alkaloids. In various plant species accumulate alkaloids uneven. Particularly rich in alkaloids, plants of the nightshade family, and poppy. Many alkaloids (morphine, papaverine, codeine, ephedrine, quinine, strychnine, etc.) used to treat diseases of the nervous system, internal bodies and other diseases. The content of alkaloids in the same plant can vary depending on the season and where they are grown. Alkaloidosoderzhaschimi plants are celandine, barberry, mordovnik, ergot, etc.